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Formulation et évaluation de la matrice de dexaméthasone: Comprimés pour le syndrome des ovaires polykystiques (pour le traitement de Polysyst)
XAF 60346
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Prepare matrix tablets of dexamethasone for effective management of polycystic ovarian syndrome.
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Bayanin samfur
- Le but de cette étude est de préparer des comprimés matriciels de dexaméthasone, qui peuvent gérer les divers facteurs-observances et commodités du patient, gérer le temps d'administration du médicament, réduire les doses multiples de dexaméthasone, effet thérapeutique souhaité. L'approche de base dans le développement de comprimés matriciels est l'utilisation de diluants co-traités tels que la cellulose microcristalline (MCC), le stéarate de magnésium, le lactose, etc. et un polymère naturel comme la gomme adragante permettent une désintégration lente des comprimés après leur mise en place dans la cavité buccale, libérant ainsi le médicament dans l'estomac. La biodisponibilité de certains médicaments peut être diminuée en raison de l'absorption des médicaments dans la salive et également en raison de l'absorption prégastrique de la salive contenant des médicaments dispersés qui passent dans l'estomac. Dans cette étude, j'ai choisi le médicament dexaméthasone car il a une demi-vie de 4-6 heures et peut être formulé comme un médicament de type durable. La formulation du comprimé sur la base d'un lot optimisé contenait 1,6 % de dexaméthasone avec 98,4 % d'excipients. En conclusion, on peut dire que les études ont été utiles pour faire évoluer la libération prolongée ou les comprimés matriciels de dexaméthasone.
| Publisher | Editions Notre Savoir |
| Publication date | 15 Mar. 2023 |
| Language | French |
| Print length | 84 pages |
| ISBN-10 | 6205794470 |
| ISBN-13 | 978-6205794470 |
| Item weight | 136 g |
| Dimensions | 15.01 x 0.48 x 22 cm |
KWATANCEN ABUN
Formulation et évaluation de la matrice de dexaméthasone: Comprimés pour le syndrome des ovaires polykystiques (pour le traitement de Polysyst)
Tambayoyi & Amsoshi na Abokan Ciniki
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Tambaya:
What is the main benefit of these dexamethasone tablets?
Amsa: They manage polycystic ovarian syndrome effectively by reducing dosing frequency. -
Tambaya:
How is the medication released in the body?
Amsa: The tablets are designed for slow disintegration, allowing controlled release into the stomach. -
Tambaya:
What ingredients are used in the tablet formulation?
Amsa: The formulation includes dexamethasone and co-processed excipients like microcrystalline cellulose.
Other Branches of Medicine Editorial Review
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XAF 60346
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Fasaloli & Fa'idoji
- Formulated for the treatment of polycystic ovarian syndrome.
- Reduces multiple doses with effective management of medication timing.
- Utilizes co-processed excipients for enhanced tablet effects.
- Features slow disintegration for controlled medication release.
- Contains 1.6% dexamethasone, optimized for sustained action.
- Studies demonstrate the benefits of extended-release formulation.
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